OC21.02: * Fetal abnormalities associated with increased nuchal translucency versus cell-free fetal DNA
نویسندگان
چکیده
منابع مشابه
Nuchal translucency: an ultrasound marker for fetal chromosomal abnormalities.
CONTEXT The literature shows an association between several ultrasound markers and chromosome abnormality. Among these, measurement of nuchal translucency has been indicated as a screening method for aneuploidy. The trisomy of chromosome 21 has been most evaluated. OBJECTIVE To define the best fixed cutoff point for nuchal translucency, with the assistance of the ROC curve, and its accuracy i...
متن کاملIncreased fetal nuchal translucency at 11-14 weeks.
Nuchal translucency (NT) is the sonographic appearance of a subcutaneous collection of fluid behind the fetal neck. The measurement of fetal NT thickness at the 11-14-week scan has been combined with maternal age to provide an effective method of screening for trisomy 21; for an invasive testing rate of 5%, about 75% of trisomic pregnancies can be identified. When maternal serum free-beta human...
متن کاملIs high fetal nuchal translucency associated with submicroscopic chromosomal abnormalities on array CGH?
OBJECTIVE To examine the possible association between high fetal nuchal translucency thickness (NT) and pathogenic chromosomal copy number variants (CNVs) detected by array comparative genomic hybridization (CGH) in pregnancies with normal fetal karyotype. METHODS Array CGH was carried out in stored samples of chorionic villi from 215 singleton pregnancies resulting in live births in which ch...
متن کاملFetal nuchal translucency scan in Nigeria
INTRODUCTION To evaluate the performance of first trimester nuchal translucency scan screening among pregnant women in Nigeria. METHODS A prospective observational and questionnaire based study involving 510 pregnant women between 11(+0) and 13(+6) weeks. Routine counselling and nuchal translucency measurement was conducted using the FMF, London guidelines. Chorionic villous sampling was done...
متن کاملImage Classification for Ultrasound Fetal Images with Increased Nuchal Translucency during First Trimester Using SVM Classifier
Increased Nuchal Translucency is an indicator of increased risk for Down syndrome, which is identified by measuring Nuchal Translucency from ultrasound fetal images during 11 to 13 weeks of gestation. Increased NT is associated with chromosomal abnormalities. In this study an efficient classification system based on Discrete Wavelet Transform (DWT) is proposed to detect the normal and abnormal ...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics & Gynecology
سال: 2017
ISSN: 0960-7692
DOI: 10.1002/uog.17681